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MIGNAR 50 mg Tablet
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VOTRIENT 400 mg Tablet
Uses of VOTRIENT 400 mg Tablet
VOTRIENT; to treat renal cell carcinoma and soft tissue sarcoma.
How it Work
Pazopanib (trade name Votrient) is a potent and selective multi-targeted receptor tyrosine kinase inhibitor that blocks tumour growth and inhibits angiogenesis
Common Side Effects
Common side effects include; Acne-like rash is reported very commonly. Other common adverse effects include: diarrhoea, nausea, vomiting, anorexia, hair loss.
Moreover,
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*Follow your doctor’s advice.
*Always take medicine after food.
*Take the medicine with water.
Fast Fact
As Pazopanib is a selective chemotherapeutic agent, its tolerability profile is better than previous cytotoxic agents. Adverse drug reactions (ADRs) are acceptable for a potentially fatal disease.
Frequently Asked Question
What kind of drug is Votrient?
Pazopanib is used to treat kidney cancer. It may also be used to treat certain other types of cancer (soft tissue sarcoma). Pazopanib belongs to a class of drugs known as tyrosine kinase inhibitors. It works by decreasing the blood supply to the cancer tumor to slow tumor growth.
What drugs interact with Imatinib?
there may be an interaction between Imatinib and any of the following:
- clarithromycin, chloramphenicol, ketoconazole, ritonavir and nefazodone.
- itraconazole, clarithromycin, grapefruit juice.
- simvastatin, ciclosporin, pimozide, warfarin, metoprolol.
- paracetamol.
Is imatinib cytotoxic?
Imatinib is a cytotoxic drug which works by inhibiting the growth of abnormal cells in Philadelphia chromosome-positive acute lymphoblastic leukaemia. In this condition, the white blood cells start growing out of control so Imatinib is used to inhibit the growth of these cells.
Common combination chemotherapy regimens
| Cancer type | Drugs |
|---|---|
| Breast cancer | Cyclophosphamide, methotrexate, 5-fluorouracil, Doxorubicin, Gefitinib |
| Hodgkin’s disease | Docetaxel, doxorubicin, cyclophosphamide, Doxorubicin, bleomycin, vinblastine, dacarbazine |
| Non-Hodgkin’s lymphoma | Cyclophosphamide, doxorubicin, vincristine, prednisolone |
| Germ cell tumor | Bleomycin, etoposide, cisplatin, |
| Stomach cancer | Epirubicin, cisplatin, capecitabine, 5-fluorouracil |
| Bladder cancer | Methotrexate, vincristine, doxorubicin, cisplatin |
| Lung cancer | Cyclophosphamide, doxorubicin, vincristine, Gefitinib, Erlotinib |
| Colorectal cancer | 5-fluorouracil, folinic acid, oxaliplatin |
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