NERVUP Injection
NERVUP; In the treatment of peripheral neuropathy, diabetic neuropathy, and B12 deficiency. Hence as nerve supplements.
Methylcobalamin that is ingested is not used directly as a cofactor but the first change by MMACHC into cob(II)alamin. Cob(II)alamin is then later transforming into the other 2 forms, adenosylcobalamin, and methylcobalamin for use as cofactors. That is, methylcobalamin is first dealkylated and then regenerated.
Alpha-lipoic acid seems to help prevent certain kinds of cell damage in the body, and also restores vitamin levels such as vitamin E and vitamin C. There is also evidence that alpha-lipoic acid can improve the function and conduction of neurons in diabetes.
Common side effects include;
A lack of methylcobalamin can lead to megaloblastic anemia and subacute combined degeneration of the spinal cord.
Moreover,
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*Follow your doctor’s advice.
*Always take medicine after food.
*Take the medicine with water.
Fast Fact
Cobalamin, a form of vitamin B12
Methylcobalamin (mecobalamin, MeCbl, or MeB12) is a cobalamin, a form of vitamin B12. It differs from cyanocobalamin in that the cyano at the cobalt is replaced with a methyl group. On the other hanMethylcobalamin features an octahedral cobalt(III) center and as bright red crystals
Methylcobalamin circulates through the bloodstream and is one of two naturally-occurring coenzyme forms of vitamin B12 that the body utilizes. so as Adenosylcobalamin is the other form sometimes used in the dietary supplement industry.
Vitamin B12 is naturally found in animal products, including fish, meat, poultry, eggs, milk, and milk products. Vitamin B12 is generally not present in plant foods, but fortified breakfast cereals are a readily available source of vitamin B12with high bioavailability for vegetarians.
Food Sources;
Solubility and Stability of Vitamins
| Vitamin | Soluble in Water | Stable to Air Exposure | Stable to Light Exposure | Stable to Heat Exposure |
|---|---|---|---|---|
| Vitamin A | no | partially | partially | relatively stable |
| Vitamin C | very unstable | yes | yes | yes |
| Vitamin D | no | no | no | no |
| Vitamin E | no | yes | yes | no |
| Vitamin K | no | no | yes | no |
| Thiamine (B1) | highly | no | Ξ | > 100 °C |
| Riboflavin (B2) | slightly | no | in solution | no |
| Niacin (B3) | yes | no | no | no |
| Pantothenic Acid (B5) | quite stable | Ξ | no | yes |
| Vitamin B6 | yes | Ξ | yes | Ξ |
| Biotin (B7) | somewhat | Ξ | Ξ | no |
| Folic Acid (B9) | yes | Ξ | when dry | at high temp |
| Vitamin B12 | yes | Ξ | yes | no |
Digestive
Vitamin D3
Diabetes
Methylcobalamin Mecobalamin
Metoprolol and Hydrochlorothiazide
Metformin and Glimepiride
Cold and Flu
Metoprolol and Hydrochlorothiazide
ESTIBASE Capsule 
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